Cortical laminar necrosis following myocardial infarction

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• 作者：Simona Lattanzi ; ^{alfierelattanzisimona@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Mauro Silvestrini ; Leandro Provinciali
• 关键词：Stroke ; Cerebrovascular disease ; Clinical neurology
• 刊名：Neurologia i Neurochirurgia Polska
• 出版年：2016
• 出版时间：July-August 2016
• 年：2016
• 卷：50
• 期：4
• 页码：271-274
• 全文大小：564 K

文摘

The cortical laminar necrosis (CLN) is a permanent injury characterized by the selective delayed necrosis of the cerebral cortex, mainly of the third layer, and usually greater in the depths and sides of the sulci than over the crest of the gyri. The damage involves all cellular components – either neurons, glia cells and blood vessels – and results in a focal cortical band of pan-necrosis detectable in late sub-acute or chronic stages of reduced energy supply to the brain. The CLN has been described in different conditions as hypoxia, hypoglycemia and status epilepticus. At brain CT or MR scans it appears with pathognomonic highly hyperdense or T1-hyperintense lesions following the gyral anatomy of the cerebral cortex. We reported a case of CLN associated to myocardial infarct and discussed the underlying mechanisms.