Direct evidence for role of anti-saliva antibodies against salivary gland homogenate of P. argentipes in modulation of protective Th1-immune response against Leishmania donovani
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- 作者：Pushpanjali ; Ajit K. Thakur ; Bidyut Purkait ; Fauzia Jamal ; Manish K. Singh ; Ghufran Ahmed ; Sanjiva Bimal ; Vijay Kumar ; Subhankar K. Singh ; Srikant Keshri ; Pradeep Das ; Shyam Narayan ; drshyamnarayan@rediffmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：SGH ; Anthroponotic transmission ; Anti-Saliva antibodies ; Cytokines
- 刊名：Cytokine
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：86
- 期：Complete
- 页码：79-85
- 全文大小：1304 K
文摘
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Immunogenicity of SGH less explored in VL where LD infection occurs after inoculation of parasites by
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SGH is instrumental in establishment of LD infection.
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Antibody against saliva of
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Anti-SGH antibody has ability to boost anti-Leishmanial Mϕ function and restrict Ld infection.
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A passive sensitization of host with SGH directed antibody may be a strategy for VL control.