Three new alkaloids from the twigs of Cassia siamea and their bioactivities
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- 作者：Hai-Yan Wua ; Wei-Yao Hub ; Qiang Liub ; Zhen-Hua Yub ; Jian-Bo Zhanb ; Ke-Liang Yanb ; Ye-De Wanga ; Kun Zhoua ; Wei Donga ; Yin-Ke Lia ; Min Zhoua ; zhouminynun@163.com" class="auth_mail" title="E-mail the corresponding author ; Qiu-Fen Hua ; huqiufena@aliyun.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tricyclic alkaloid ; Cassia siamea ; Anti-tobacco mosaic virus activity ; Cytotoxicity
- 刊名：Phytochemistry Letters
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：15
- 期：Complete
- 页码：121-124
- 全文大小：349 K
文摘
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Three new (1–3) and three known (4–6) alkaloids were isolated.
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Compounds 1–6 were evaluated for their anti-TMV activities and cytotoxicity.
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Compound 3 exhibited high anti-TMV activity with inhibition rate of 34.5%.
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Compounds 2–6 showed weak activity with IC50 values ranging from 2.8 to 9.4 μM.