Step-by-step electrodeposition of a high-performance Prussian blue-gold nanocomposite for H₂O₂ sensing and glucose biosensing

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• 作者：Long Chao ; Wen Wang ; Mengzhen Dai ; Yixuan Ma ; Lingen Sun ; Xiaoli Qin ; Qingji Xie ; ^{xieqj@hunnu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Step-by-step electrodeposition ; Prussian blue-gold nanocomposite ; Determination of H2O2 ; Glucose oxidase-polydopamine-Pt nanoparticles bionanocomposite ; Biosensing of glucose
• 刊名：Journal of Electroanalytical Chemistry
• 出版年：2016
• 出版时间：1 October 2016
• 年：2016
• 卷：778
• 期：Complete
• 页码：66-73
• 全文大小：2013 K

文摘

A Prussian blue (PB)-gold nanocomposite ((PB-Au)_x, where x denotes the number of PB-Au bilayer) is prepared, by step-by-step electrodeposition of PB and gold on a glassy carbon electrode (GCE). The optimized (PB-Au)₂/GCE exhibits excellent electrocatalytic activity for electroreduction of H₂O₂, and the cathodic current at − 0.05 V responds linearly to H₂O₂ concentration up to 3.88 mM with a sensitivity of 1.32 mA mM^− 1 cm^− 2, which outperforms the gold-PB nanocomposites electrodeposited through other reported protocols. Moreover, a glucose oxidase (GOx)-polydopamine (PDA)-Pt nanoparticles (PtNPs) bionanocomposite is synthesized through chemical oxidation of dopamine by sodium chloroplatinate in the presence of GOx. A chitosan (CS)/GOx-PDA-PtNPs/(PB-Au)₂/GCE is fabricated by casting GOx-PDA-PtNPs and then CS on (PB-Au)₂/GCE. The cathodic current at − 0.05 V on this enzyme electrode responds linearly to glucose concentration from 5 μM to 0.79 mM with a sensitivity of 114 μA mM^− 1 cm^− 2 and a LOD of 0.5 μM (S/N = 3). The presented protocol can flexibly balance the high catalytic activity and the poor electron-conductance of PB for improving the electroactivity and electrocatalytic activity of PB-based films, thus yielding high-performance PB-based electrodes for low-potential determination of H₂O₂ and glucose.