Current and Upcoming Therapies for Ocular Surface Chemical Injuries

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• 作者：Alireza Baradaran-Rafii ; MD¹ ; ^&lowast ; ; Medi Eslani ; MD² ; ^&lowast ; ; Zeeshan Haq ; BS² ; Ebrahim Shirzadeh ; MD¹ ; Michael J. Huvard ; MD² ; Ali R. Djalilian ; MD² ; ^{adjalili@uic.edu}
• 关键词：chemical burn ; cornea ; limbal stem cell deficiency ; ocular chemical burn ; ocular surface ; stem cell
• 刊名：The Ocular Surface
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：15
• 期：1
• 页码：48-64
• 全文大小：2466 K
• 卷排序：15

文摘

Chemical injuries frequently result in vision loss, disfigurement, and challenging ocular surface complications. Acute interventions are directed at decreasing the extent of the injury, suppressing inflammation, and promoting ocular surface re-epithelialization. Chronically, management involves controlling inflammation along with rehabilitation and reconstruction of the ocular surface. Future therapies aimed at inhibiting neovascularization and promoting ocular surface regeneration should provide more effective treatment options for the management of ocular chemical injuries.