A cholesterol biosensor based on gold nanoparticles decorated functionalized graphene nanoplatelets

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• 作者：Sasidharan Sasikala Jyothirmayee Aravind^a ; Tessy Theres Baby^a ; Thevasahayam Arockiadoss^a ; Raghavan Baby Rakhi^a ; Sundara Ramaprabhu ; ^a ; ^{ramp@iitm.ac.in"" rel=""nofollow}
• 关键词：Graphene nanoplatelets ; Nafion ; Gold nanoparticles ; Biosensor
• 刊名：Thin Solid Films
• 出版年：2011
• 出版时间：1 June 2011
• 年：2011
• 卷：519
• 期：16
• 页码：5667-5672
• 全文大小：843 K

文摘

The fabrication of a cholesterol biosensor using gold nanoparticles decorated graphene nanoplatelets has been reported. Thermally exfoliated graphene nanoplatelets act as a suitable support for the deposition of Au nanoparticles. Cholesterol biosensor electrodes have been constructed with nafion solubilized functionalized graphene nanoplatelets (f-G) as well as Au nanoparticles decorated f-G, immobilized over glassy carbon electrode. f-G and Au/f-G thin film deposited glassy carbon electrodes were further functionalized with cholesterol oxidase by physical adsorption. Au nanoparticles dispersed over f-G demonstrate the ability to substantially raise the response current. The fabricated electrodes have been tested for their electrochemical performance at a potential of 0.2 V. The fabricated Au/f-G based cholesterol biosensor exhibits sensitivity of 314 nA/μM cm² for the detection of cholesterol with a linear response up to 135 μM. Furthermore, it has been observed that the biosensor exhibits a good anti-interference ability and favorable stability over a month's period.