Relative contributions of modifiable risk factors to erectile dysfunction: Results from the Boston Area Community Health (BACH) Survey

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• 作者：Varant Kupelian ; Andre B. Araujo ; Gretchen R. Chiu ; Raymond C. Rosen ; John B. McKinlay
• 关键词：Erectile dysfunction ; Risk factors ; Prevention ; Epidemiology
• 刊名：Preventive Medicine
• 出版年：2010
• 出版时间：January-February 2010
• 年：2010
• 卷：50
• 期：1-2
• 页码：19-25
• 全文大小：479 K

文摘

class=""h4"">Objectives

The objective of this study was to determine the relative contribution of modifiable risk factors (physical activity, smoking, and alcohol consumption) to inter-subject variation in erectile dysfunction (ED).

class=""h4"">Methods

The Boston Area Community Health (BACH) Survey used a multistage stratified random sample to recruit 2301 men age 30–79 years from the city of Boston between 2002 and 2005. ED was assessed using the 5-item International Index of Erectile Function (IIEF-5). Multiple linear regression models and R² were used to determine the proportion of the variance explained by modifiable risk factors.

class=""h4"">Results

In unadjusted analyses, lifestyle factors accounted for 12.2 % of the inter-subject variability in IIEF-5 scores, comparable to the proportion explained by comorbid conditions (14.7 % ) and socioeconomic status (9 % ). Lifestyle factors were also significantly associated with age, comorbid conditions and socioeconomic status (SES). A multivariate model including all covariates associated with ED explained 29 % of the variance, with lifestyle factors accounting for 0.9 % over and above all other covariates in the model. Analyses repeated in a subgroup of 1215 men without comorbid conditions show lifestyle factors accounting for 2.5 % of the variance after accounting for all other variables in the model.

class=""h4"">Conclusions

Results of the present study demonstrate the contribution of modifiable lifestyle factors to the prevalence of ED. These results suggest a role for behavior modification in the prevention of ED.