Copper-catalysed domino reaction of 2-bromobenzylidenemalonates and 1,3-dicarbonyls for the synthesis of chromenes

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• 作者：Yotsakorn Saebang ; Vatcharin Rukachaisirikul ; Juthanat Kaeobamrung ; ^{juthanat.k@psu.ac.th}
• 关键词：Copper-catalysed domino reaction ; Ullmann-type coupling ; C(aryl)&ndash ; O bond formation ; Michael addition ; Chromenes
• 刊名：Tetrahedron Letters
• 出版年：2017
• 出版时间：11 January 2017
• 年：2017
• 卷：58
• 期：2
• 页码：168-171
• 全文大小：2276 K
• 卷排序：58

文摘

4H-Chromenes were synthesized from benzylidenemalonates and 1,3-dicarbonyls. The reactions proceed under simple reaction conditions. Michael addition and Ullmann-type coupling are two key features in the domino process. The elimination of stabilized carbanion is rationalized as the competitive reaction.