A Reduced-Intensity Conditioning Regimen for Patients with Dyskeratosis Congenita Undergoing Hematopoietic Stem Cell Transplantation
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- 作者：Adam S. Nelson1 ; Adam.nelson@cchmc.org" class="auth_mail" title="E-mail the corresponding author ; Rebecca A. Marsh1 ; Kasiani C. Myers1 ; Stella M. Davies1 ; Sonata Jodele1 ; Tracey A. O'Brien2 ; Parinda A. Mehta1
- 关键词：Dyskeratosis congenita ; Hematopoietic stem cell transplantation ; Reduced-intensity conditioning
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：22
- 期：5
- 页码：884-888
- 全文大小：314 K
文摘
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Reduced-intensity conditioning without radiation for dyskeratosis congenita improves outcomes
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Engraftment is maintained in the absence of radiation
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Acceptable toxicity and overall survival are achieved with reduced-intensity conditioning
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Potential for reduced long-term toxicity with a nonradiation reduced-intensity conditioning regimen exists