AMPK is involved in the differential neonatal performance of chicks hatching at different time
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- 作者：Yufeng Wanga ; Johan Buysea ; johan.buyse@biw.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ; Zhigang Songb ; Eddy Decuyperea ; Nadia Everaerta ; c
- 关键词：ACC ; acetyl-CoA carboxylase ; AgRP ; agouti-related peptide ; AMPK ; AMP-activated protein kinase ; CRH ; corticotropin-releasing hormone ; GS ; glycogen synthase ; HIF1α ; hypoxia-inducible factor 1-alpha ; FAS ; fatty acid synthase ; FTO ; fat mass and obesity-associated ; LKB1 ; liver kinase B1 ; NPY ; neuropeptide Y ; POMC ; pro-opiomelanocortin ; SREBP-1 ; sterol regulatory element-binding transcription factor 1 ; TBP ; TATA-box binding protein
- 刊名：General and Comparative Endocrinology
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：228
- 期：Complete
- 页码：53-59
- 全文大小：529 K
文摘
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Hypothalamic NPY and AgRP mRNA levels were higher in the late hatchers as compared to the early hatchers.
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Hepatic phospho-GS of the late hatchers were lower than that of their early counterparts.
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Hypothalamic AMPKα1 gene expression was higher in the later hatched chicks.
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Hepatic AMPKα2 mRNA level and the activity of AMPKα was significantly lower in the late hatchers.