Interferon gamma response to Mycobacterium avium subsp. paratuberculosis specific lipopentapeptide antigen L5P in cattle
详细信息 查看全文
- 作者：Sé ; bastien Holberta ; sebastien.holbert@tours.inra.fr" class="auth_mail" title="E-mail the corresponding author ; Maxime Brangera ; maxime.branger@tours.inra.fr" class="auth_mail" title="E-mail the corresponding author ; Armel Souriaua ; a-souriau@orange.fr" class="auth_mail" title="E-mail the corresponding author ; Bé ; ré ; nice Lamoureuxb ; blamoureux@gdma36.fr" class="auth_mail" title="E-mail the corresponding author ; Christelle Ganneauc ; d ; christelle.ganneau@pasteur.fr" class="auth_mail" title="E-mail the corresponding author ; Gaë ; lle Richarda ; gaelle703@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Thierry Cocharda ; thierry.cochard@tours.inra.fr" class="auth_mail" title="E-mail the corresponding author ; Christophe Tholoniatb ; ctholoniat@gdma36.fr" class="auth_mail" title="E-mail the corresponding author ; Sylvie Bayc ; d ; sylvie.bay@pasteur.fr" class="auth_mail" title="E-mail the corresponding author ; Nathalie Wintera ; nathalie.winter@tours.inra.fr" class="auth_mail" title="E-mail the corresponding author ; Jean Louis Moyene ; jl.moyen@dordogne.fr" class="auth_mail" title="E-mail the corresponding author ; Franck Bieta ; franck.biet@tours.inra.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mycobacterium avium subsp. paratuberculosis ; Paratuberculosis ; Johne's disease ; Antigen ; Lipopeptide ; Lipopentapeptide ; L5P ; IFN-纬 release assay ; IGRA ; Cell mediated immune response
- 刊名：Research in Veterinary Science
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：102
- 期：Complete
- 页码：118-121
- 全文大小：307 K
文摘
- •
Non-infected, Map infected and Mycobacterium bovis infected cattle herds recruited to explore whole blood CMI response
- •
Chemically synthetized Map-specific antigen L5P tested in IGRA
- •
L5P can induce CMI responses which can be quantified by assaying IFN-纬 release in whole blood stimulation.