Characterization of Acr2, an H-NS-like protein encoded on A/C2-type plasmids
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文摘

Binding sites of Acr2 were defined and differentially expressed genes were identified in strains lacking Acr2.

Acr2 was found to bind multiple loci on the plasmid as well as sites on the host bacterial chromosome.

Acr2 shares a DNA binding motif with other H-NS-like homologs, critical for its function as a repressor of IncA/C conjugation.

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