Closed-loop control of extracorporeal oxygen and carbon dioxide gas transfer

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• 作者：C. Brendle^a ; ^{brendle@hia.rwth-aachen.de} ; K.-F. Hackmack^a ; J. Kü ; hn^b ; M.N. Wardeh^c ; T. Janisch^d ; R. Kopp^c ; R. Rossaint^c ; A. Stollenwerk^b ; S. Kowalewski^b ; S. Leonhardt^a ; M. Walter^a ; B. Misgeld^a
• 关键词：Biomedical application ; MIMO system ; Decentralized H&infin ; control ; Extracorporeal membrane oxygenation ; Acute respiratory distress syndrome
• 刊名：Control Engineering Practice
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：59
• 期：Complete
• 页码：173-182
• 全文大小：1314 K
• 卷排序：59

文摘

Continuous control of extracorporeal O2 and CO2 gas transfer rates is proposed. Only non-invasive sensors (e.g. in gas phase) are used (no blood gas analysis). A decentralized closed-loop control system with robust controllers is presented. Control system was evaluated in silico and in vivo. Results suggest that application for physiological target control is feasible.