Chlorogenic acid rescues sensorineural auditory function in a diabetic animal model

详细信息    查看全文

• 作者：Bin Na Hong^a ; ^b ; Youn Hee Nam^a ; ^c ; Sang Ho Woo^a ; ^c ; Tong Ho Kang^a ; ^c ; ^{panjae@khu.ac.kr}
• 关键词：DM ; diabetes mellitus ; CA ; chlorogenic acid ; ABRs ; auditory brainstem responses ; AMLRs ; auditory middle latency responses ; TEOAE ; transient evoked optoacoustic emission ; SEM ; scanning electron microscope ; GLM ; glimepiride ; AIZL ; alloxan induced zebrafish larvae
• 刊名：Neuroscience Letters
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：640
• 期：Complete
• 页码：64-69
• 全文大小：3073 K
• 卷排序：640

文摘

CA may improve damaged peripheral and central auditory function in the DM mouse model. CA may aid in the recovery of OHCs damage in the DM mice cochlea and otic hair cells damage in AIZL. The efficacy of CA in diabetic sensorineural auditory dysfunctions seems to be an independent action of CA, rather than an hypoglycemiant effect.