Paternal calorie restriction prior to conception alters anxiety-like behavior of the adult rat progeny
详细信息 查看全文
- 作者：Antonina Govica ; b ; antonina.govic@rmit.edu.au" class="auth_mail" title="E-mail the corresponding author ; Jim Penmana ; Amanda H. Tammerb ; Antonio G. Paolinia ; b ; c
- 关键词：Paternal programming ; Calorie restriction ; Corticosterone ; Anxiety-like behavior ; HPA axis ; Leptin
- 刊名：Psychoneuroendocrinology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：64
- 期：Complete
- 页码：1-11
- 全文大小：1661 K
文摘
- •
Paternal influences on adult offspring anxiety-like behavior was examined.
- •
Paternal calorie restriction (CR) decreased the anxiety behavior of the progeny.
- •
Food intake, body weight and leptin levels was reduced in the offspring of CR males.
- •
Paternal corticosterone treatment failed to alter offspring behavior.
- •
CR offspring exhibit a profile adapted to an environment of limited food supply.