Different calorie restriction treatments have similar anti-seizure efficacy
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- 作者：Andrea Viggianoa ; aviggiano@unisa.it" class="auth_mail" title="E-mail the corresponding author ; Raffaele Pillab ; c ; raf.pilla@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Patrick Arnoldd ; Marcellino Mondae ; marcellino.monda@unina2.it" class="auth_mail" title="E-mail the corresponding author ; Dominic D&rsquo ; Agostinob ; ddagosti@health.usf.edu" class="auth_mail" title="E-mail the corresponding author ; Pio Zeppaa ; Giangennaro Coppolaa ; f
- 关键词：Calorie restriction ; Ketogenic diet ; Synthetic ketone ; Seizure
- 刊名：Seizure
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：45-49
- 全文大小：986 K
文摘
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The anti-seizure efficacy of a prolonged administration of a synthetic ketone has been evaluated.
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The prolonged administration of 1,3-butanediol acetoacetate diester by gavage produces calorie restriction in rats.
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Gavage treatments in rats produce calorie restriction and anti-seizure effects similar to that of a ketogenic diet.