Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

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• 作者：Ahmad Al-Attar^a ; Steven R. Presnell^a ; Charlotte A. Peterson^b ; D. Travis Thomas^c ; Charles T. Lutz^a ; ^d ; ^{charles.lutz@uky.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：NK cell ; Ageing ; Cytomegalovirus ; T cell ; Sex factors ; Vitamin D ; C-reactive protein ; Adiponectin ; IL-15 ; Sphingosine-1-phosphate ; Retinol binding protein-4
• 刊名：Data in Brief
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：8
• 期：Complete
• 页码：536-544
• 全文大小：199 K

文摘

We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56^dim NK cell responses to a variety of stimuli and with CD56^bright/CD56^dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)−4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56^dim NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].