- 作者：Patricia Becerra ; DDS&lowast ; ; Domenico Ricucci ; MD ; DDS&dagger ; ; dricucci@libero.it" class="auth_mail" title="E-mail the corresponding author ; Simona Loghin ; DDS&dagger ; ; Jennifer L. Gibbs ; MAS ; DDS ; PhD&Dagger ; ; Louis M. Lin ; BDS ; DMD ; PhD&Dagger ;
- 关键词：Bone-like tissue ; cementum-like tissue ; chronic apical abscess ; human immature permanent tooth ; revascularization/revitalization
- 刊名：Journal of Endodontics
- 出版年：2014
- 出版时间：January 2014
- 年：2014
- 卷：40
- 期：1
- 页码：133-139
- 全文大小：2703 K
Methods
An immature mandibular premolar with infected necrotic pulp and a chronic apical abscess was treated with revascularization/revitalization procedures. At both the 18-month and 2-year follow-up visits, radiographic examination showed complete resolution of the periapical lesion, narrowing of the root apex without root lengthening, and minimal thickening of the canal walls. The revascularized/revitalized tooth was removed because of orthodontic treatment and processed for histologic examination.
Results
The large canal space of revascularized/revitalized tooth was not empty and filled with fibrous connective tissue. The apical closure was caused by cementum deposition without dentin. Some cementum-like tissue was formed on the canal dentin walls. Inflammatory cells were observed in the coronal and middle third of revascularized/revitalized tissue.
Conclusions
In the present case, the tissue formed in the canal of a human revascularized/revitalized tooth was soft connective tissue similar to that in the periodontal ligament and cementum-like or bone-like hard tissue, which is comparable with the histology observed in the canals of teeth from animal models of revascularization/revitalization.