Structural analysis and anti-obesity effect of a pectic polysaccharide isolated from Korean mulberry fruit Oddi (Morus alba L.)
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- 作者：Ji Won Choia ; 1 ; Andriy Synytsyab ; 1 ; Peter Capekc ; Roman Blehab ; Radek Pohld ; Yong Il Parka ; yongil382@catholic.ac.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mulberry fruit ; Pectic polysaccharide ; Structure ; Pre-adipocytes ; Apoptosis
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：1 August 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：187-196
- 全文大小：1896 K
文摘
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Mulberry polysaccharide JS-MP-1 was defined as a rhamnogalacturonan type I (RG I) polymer.
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JS-MP-1 carries arabinan and arabinogalactan (AG II) side chains.
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JS-MP-1 dose-dependently reduces the viability of 3T3-L1 pre-adipocyte cells.
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JS-MP-1 induces mitochondrial dysfunction and apoptosis in pre-adipocyte cells.
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JS-MP-1 has in vitro anti-obesity effects via inhibition of adipocyte proliferation.