The presence of a single MALDI-TOF mass spectral peak predicts methicillin resistance in staphylococci
详细信息 查看全文
- 作者：Daniel D. Rhoads ; Daniel.Rhoads@case.edu" class="auth_mail" title="E-mail the corresponding author ; danrhoads@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Hannah Wang wangh@ccf.org" class="auth_mail" title="E-mail the corresponding author ; James Karichu karichj@ccf.org" class="auth_mail" title="E-mail the corresponding author ; Sandra S. Richter richtes@ccf.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：MRSA ; MALDI-TOF ; mecA ; Strain typing ; PFGE ; Antimicrobial resistance
- 刊名：Diagnostic Microbiology & Infectious Disease
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：86
- 期：3
- 页码：257-261
- 全文大小：427 K
文摘
- •
Routine clinical MALDI-TOF MS can detect PSM-mec at 2415 m/z in staphylococci.
- •
PSM-mec detection has a high positive predictive value for inferring mecA carriage.
- •
Most S. aureus and S. epidermidis that carry mecA lack detectable levels of PSM-mec.