Biocompatible hydrogelators based on bile acid ethyl amides
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- 作者：Riikka Kuosmanena ; Rakesh Puttreddya ; Roosa-Maria Willmana ; Ilkka Ä ; ijä ; lä ; inena ; Adé ; la Galandá ; ková ; b ; Jitka Ulrichová ; b ; Hannu Saloa ; Kari Rissanena ; Elina Sievä ; nena ; elina.i.sievanen@jyu.fi" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bile acid ; Amide ; Self-assembly ; Supramolecular hydrogel ; Biocompatibility
- 刊名：Steroids
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：108
- 期：Complete
- 页码：7-16
- 全文大小：1698 K
文摘
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Four new bile acid ethyl amide derivatives were synthesized and characterized in detail.
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Several gel systems, including for the first time bile acid alkyl amide derived hydrogels, were formed.
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The properties of the gels were investigated, and the toxicity of the compounds determined.
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The XRD-derived packing patterns may reveal the gel state assembly of the molecules.
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The biocompatibility of these and other bile acid-based hydrogels may be used in biomedicine.