The role of genes involved in stress, neural plasticity, and brain circuitry in depressive phenotypes: Convergent findings in a mouse model of neglect
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- 作者：Janitza L. Montalvo-Ortiza ; Kelly A. Bordnerb ; Becky C. Carlylea ; Joel Gelerntera ; c ; Arthur A. Simend ; Joan Kaufman ; PhD.e ; f ; joan.kaufman@kennedykrieger.org" class="auth_mail" title="E-mail the corresponding author (Director of Research Associate Professor)
- 关键词：Neglect ; Depression ; Methylation ; DNA-binding protein inhibitor ID-3 (ID3) ; Glutamate NMDA receptor (GRIN1) ; Tubulin polymerization promoting protein (TPPP)
- 刊名：Behavioural Brain Research
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：315
- 期：Complete
- 页码：71-74
- 全文大小：551 K
文摘
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mPFC gene expression examined in mouse model of maternal neglect. (Characters with spaces: 67).
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Stress (ID3), synaptic plasticity (GRIN1) and myelin related (TPPP) genes explored. (Characters with spaces: 85).
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Genes selected to validate results obtained from peripheral samples in children. (Characters with spaces: 82).
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ID3, GRIN1 and TPPP expression predict depression and anxiety behaviors in mice. (Characters with spaces: 82).