Phylogeographic Analysis of Haplogroup E3b (E-M215) Y Chromosomes Reveals Multiple Migratory Events Within and Out Of Africa

详细信息    查看全文

• 作者：Fulvio Cruciani ; Roberta La Fratta ; Piero Santolamazza ; Daniele Sellitto ; Roberto Pascone ; Pedro Moral ; Elizabeth Watson ; Valentina Guida ; Eliane Beraud Colomb ; Boriana Zaharova ; Joã ; o Lavinha ; Giuseppe Vona ; Rashid Aman ; Francesco Calì ; Nejat Akar ; Martin Richards ; Antonio Torroni ; Andrea
• 刊名：The American Journal of Human Genetics
• 出版年：2004
• 出版时间：May 2004
• 年：2004
• 卷：74
• 期：5
• 页码：1014-1022
• 全文大小：1207 K

文摘

We explored the phylogeography of human Y-chromosomal haplogroup E3b by analyzing 3,401 individuals from five continents. Our data refine the phylogeny of the entire haplogroup, which appears as a collection of lineages with very different evolutionary histories, and reveal signatures of several distinct processes of migrations and/or recurrent gene flow that occurred in Africa and western Eurasia over the past 25,000 years. In Europe, the overall frequency pattern of haplogroup E-M78 does not support the hypothesis of a uniform spread of people from a single parental Near Eastern population. The distribution of E-M81 chromosomes in Africa closely matches the present area of distribution of Berber-speaking populations on the continent, suggesting a close haplogroup–ethnic group parallelism. E-M34 chromosomes were more likely introduced in Ethiopia from the Near East. In conclusion, the present study shows that earlier work based on fewer Y-chromosome markers led to rather simple historical interpretations and highlights the fact that many population-genetic analyses are not robust to a poorly resolved phylogeny.