RNA Bind-n-Seq: Quantitative Assessment of the Sequence and Structural Binding Specificity of RNA Binding Proteins
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- 作者：Nicole Lambert1 ; 5 ; Alex Robertson1 ; 2 ; 5 ; Mohini Jangi1 ; Sean McGeary1 ; 4 ; Phillip A. Sharp1 ; 3 ; Christopher B. Burge1 ; 3 ; cburge@mit.edu" class="auth_mail
- 刊名：Molecular Cell
- 出版年：5 June 2014
- 年：2014
- 卷：54
- 期：5
- 页码：887-900
- 全文大小：3082 K
文摘
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RBNS is a method for comprehensive, quantitative mapping of RNA binding specificity
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RBNS identifies multiple motifs recognized by RBFOX2, CELF1, and MBNL1 proteins
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RNA structure inhibits binding, except MBNL1 tolerates G/C pairing in UGC motifs
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RBNS distinguishes subsets of functional and nonfunctional CLIP-seq motifs