- 作者：Alessandro Buda ; alessandro.buda@fastwebnet.it ; Robert Fruscio ; Cecilia Pirovano ; Mauro Signorelli ; Marta Betti ; Rodolfo Milani
- 关键词：Gynecologic malignancy ; Inguinofemoral groin dissection ; Postoperative complications ; Surgical patch
- 刊名：International Journal of Gynecology and Obstetrics
- 出版年：2012
- 出版时间：June, 2012
- 年：2012
- 卷：117
- 期：3
- 页码：217-219
- 全文大小：181 K
Objective
To evaluate the effect of TachoSil in preventing postoperative complications after groin dissection performed for primary or recurrent gynecologic malignancy.Methods
In a case-control analysis, the incidence of postoperative complications¡ªincluding lymphocyst formation, wound breakdown and/or infection, and chronic lymphedema¡ªwas examined among 8 patients who received TachoSil and 16 controls (standard technique) treated for vulvar cancer or recurrent ovarian/breast cancer at San Gerardo Hospital, Monza, Italy, from 2008 to 2011.
Results
Thirty-eight inguinal dissections were performed in the 24 patients. Bilateral groin dissection was performed in 14 patients (n = 4 in the study group; n = 10 in the control group). Patients in the study group had a lower mean daily drainage volume than those in the control group (133 mL [range, 50-356 mL] vs 320 mL [range, 67-472 mL]; P < 0.001) and a lower incidence of lymphocyst requiring drainage (25.0 % vs 62.5 % ), cellulitis (12.0 % vs 25.0 % ), and wound infection (0.0 % vs 25.0 % ).
Conclusion
The use of TachoSil seems to be effective in reducing the rate of postoperative complications after inguinofemoral lymphadenectomy in cases of gynecologic malignancy.