Early tumour response as a survival predictor in previously- treated patients receiving triplet hepatic artery infusion and intravenous cetuximab for unresectable liver metastases from wild-type KRAS colorectal cancer
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- 作者：Mohamed Bouchahdaa ; b ; c ; Valé ; rie Boiged ; Denis Smithe ; Abdoulaye Karaboué ; b ; f ; Michel Ducreuxd ; Mohamed Hebbarg ; Cé ; line Lepè ; reh ; Christian Focani ; Rosine Guimbaudj ; Pasquale Innominatoa ; b ; m ; Sameh Awada ; Carlos Carvalhok ; Salvatore Tumolol ; Stephanie Truantg ; Thierry De Baered ; Denis Castainga ; Philippe Rougierh ; Jean-Franç ; ois Morè ; rea ; Julien Taiebh ; René ; Adama ; b ; Francis Lé ; via ; b ; m ; F.Levi@warwick.ac.uk" class="auth_mail" title="E-mail the corresponding author ; on behalf of ARTBC International
- 关键词：Early tumour response ; Colorectal cancer ; Liver metastases ; Hepatic artery infusion ; Triplet chemotherapy
- 刊名：European Journal of Cancer
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：68
- 期：Complete
- 页码：163-172
- 全文大小：953 K
文摘
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The rate of conversion-to-resection of liver metastases was tripled after early tumour response.
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The median overall survival of early responders was 14 months longer than that of the late or non-responders.
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Early response on hepatic artery infusion should critically optimise curative intent medicosurgical strategies.