This hospital-based clinical and microbiological Hib disease surveillance in 3 hospitals in the western region of The Gambia was undertaken between October 2007 and December 2010 applying the same methods used in a previous Hib vaccine effectiveness study in 1997-2002.
The annual incidences of Hib meningitis and all invasive Hib disease in children aged <5 years remained below 5 cases per 100?000 children during 2008-2010. The median age of patients with any invasive Hib disease was 5 months.
Hib conjugate vaccination as a primary 3-dose course in The Gambia remains highly effective in controlling invasive Hib disease, and current data do not support the introduction of a booster dose.