A new LPG nano-optrode for Tg detection, a marker of differentiated thyroid cancer.
A reflection-type LPG working in “transition-mode” as highly sensitive RI transducer.
The RT-LPG is functionalized with a high affinity anti-Tg monoclonal antibody.
Analyte capture confirmed for the first time by a parallel on fiber ELISA-like assay.
Linear biosensor response between 0-4 ng/mL; saturation occurs for higher Tg levels.