A resonance light scattering sensor based on bioinspired molecularly imprinted polymers for selective detection of papain at trace levels
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- 作者：Bin Yang ; Sifang Lv ; Feng Chen ; Chan Liu ; Changqun Cai ; cai_mao3@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Chunyan Chen ; Xiaoming Chen
- 关键词：Resonance light scattering ; Protein-imprinted polymer nanoparticles ; Specific detection ; Mussel-inspired bionic polydopamine ; Papain
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：17 March 2016
- 年：2016
- 卷：912
- 期：Complete
- 页码：125-132
- 全文大小：1552 K
文摘
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A MIPs-based RLS sensor is developed for the first time to recognize protein.
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The bio-inspired PDA coated SiO2 NPs reduce the cytotoxicity in protein detection.
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Highly selective and sensitive are obtained and the detection limit is 0.63 nM.
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The sensor can be applied to some systems that can't be detected by fluorescence.