Isolated Aerobic Exercise and Weight Loss: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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• 作者：Adrian Thorogood BSc^a ; ^b ; Salvatore Mottillo BSc^a ; ^b ; ^c ; Avi Shimony MD^a ; ^b ; Kristian B. Filion PhD^d ; Lawrence Joseph PhD^e ; ^f ; Jacques Genest MD^g ; Louise Pilote MD ; MPH ; PhD^e ; ^f ; ^h ; Paul Poirier MD ; PhDⁱ ; Ernesto L. Schiffrin MD ; PhD^b ; ^j ; Mark J. Eisenberg MD ; MPH^a ; ^b ; ^e ; ^{mark.eisenberg@mcgill.ca"" rel=""nofollow}
• 关键词：Abdominal obesity ; Aerobic exercise ; Cardiovascular risk ; Meta-analysis ; Obesity ; Weight loss
• 刊名：The American Journal of Medicine
• 出版年：2011
• 出版时间：August 2011
• 年：2011
• 卷：124
• 期：8
• 页码：747-755
• 全文大小：989 K

文摘

lass=""h4"">Background

Aerobic exercise is a common nonpharmacological intervention for the management of obesity. However, the efficacy of isolated aerobic exercise at promoting weight loss is unclear. We conducted a systematic review and meta-analysis to evaluate the efficacy of isolated aerobic exercise programs in overweight and obese populations.

lass=""h4"">Methods

We searched for published randomized controlled trial reports of aerobic exercise through January 20, 2010. Trials with an isolated aerobic exercise intervention were included. A random-effect model was used to synthesize the results of each intervention.

lass=""h4"">Results

We identified 14 trials involving 1847 patients. The duration of aerobic exercise programs ranged from 12 weeks to 12 months. Results were pooled for programs with 6-month duration and programs with 12-month duration. Six-month programs were associated with a modest reduction in weight (weighted mean difference [WMD] = −1.6 kg; 95 % confidence interval [CI], −1.64 to −1.56) and waist circumference (WMD = −2.12 cm; 95 % CI, −2.81 to −1.44). Twelve-month programs also were associated with modest reductions in weight (WMD = −1.7 kg; 95 % CI, −2.29 to −1.11) and waist circumference (WMD = −1.95 cm; 95 % CI, −3.62 to −0.29).

lass=""h4"">Conclusion

Moderate-intensity aerobic exercise programs of 6-12 months induce a modest reduction in weight and waist circumference in overweight and obese populations. Our results show that isolated aerobic exercise is not an effective weight loss therapy in these patients. Isolated aerobic exercise provides modest benefits to blood pressure and lipid levels and may still be an effective weight loss therapy in conjunction with diets.