Comparison of apoptosis between adult worms of Schistosoma japonicum from susceptible (BALB/c mice) and less-susceptible (Wistar rats) hosts
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- 作者：Tao Wanga ; 1 ; Xiaoyong Guoa ; 1 ; Yang Honga ; Hongxiao Hana ; Xiaodan Caoa ; Yanhui Hana ; b ; Min Zhanga ; c ; Miaoli Wua ; Zhiqiang Fua ; Ke Lua ; Hao Lia ; Zhixin Zhaoa ; Jiaojiao Lina ; d ; jjlin@shvri.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：S. japonicum ; Schistosoma japonicum ; TEM ; transmission electron microscopy ; TUNEL ; fluorometric terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling ; FCM ; flow cytometry ; RT-PCR ; real-time polymerase chain reaction ; PZQ ; praziquantel ; PBS ; phosphate buffered saline ; PI ; propidium iodide ; NADH ; nicotinamide adenine dinucleotide dehydrogenase ; AIF ; apoptosis-inducing factor ; APAF ; apoptotic protease-activating factor ; API ; apoptosis inhibitor ; ATM ; ataxia telangiectasia mutated ; B
- 刊名：Gene
- 出版年：2016
- 出版时间：30 October 2016
- 年：2016
- 卷：592
- 期：1
- 页码：71-77
- 全文大小：1003 K
文摘
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TEM showed classical apoptosis phenomena in adult worms from both hosts.
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TUNEL showed more apoptosis spots in adult worms from rats than mice.
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FCM demonstrated higher apoptosis percentage in adult worms from rats than mice.
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Fifteen apoptosis-associated genes of worms from two hosts were detected by RT-PCR.