Sec-secretion and sortase-mediated anchoring of proteins in Gram-positive bacteria
详细信息 查看全文
- 作者：Olaf Schneewind ; oschnee@bsd.uchicago.edu" class="auth_mail ; Dominique Missiakas
- 关键词：Sec ; Leader peptide ; LPXTG ; Sortase ; Cell wall ; Peptidoglycan
- 刊名：Biochimica et Biophysica Acta (BBA)/Molecular Cell Research
- 出版年：August 2014
- 年：2014
- 卷：1843
- 期：8
- 页码：1687-1697
- 全文大小：967 K
文摘
- •
Cell wall anchored proteins are displayed on the surface of Gram-positive bacteria.
- •
We describe the processes involved in secretion and processing of these proteins.
- •
We describe how sortase catalyzes the covalent attachment of these proteins to peptidoglycan.
- •
We describe the physiological contributions of the four classes of known sortase enzymes.