The Inhibitory Receptor NKG2A Sustains Virus-Specific CD8+ T Cells in Response to a Lethal Poxvirus Infection
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- 作者：Aaron S. Rapaport1 ; Jill Schriewer2 ; Susan Gilfillan1 ; Ed Hembrador2 ; Ryan Crump2 ; Beatrice F. Plougastel3 ; Yaming Wang1 ; Gaelle Le Friec1 ; 6 ; Jian Gao3 ; Marina Cella1 ; Hanspeter Pircher4 ; Wayne M. Yokoyama3 ; 5 ; R. Mark L. Buller2 ; Marco Colonna1 ; mcolonna@pathology.wustl.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：virus ; cytokine ; CD8+ T cell ; NK cell ; inhibitory receptor ; NKG2A
- 刊名：Immunity
- 出版年：2015
- 出版时间：15 December 2015
- 年：2015
- 卷：43
- 期：6
- 页码：1112-1124
- 全文大小：4525 K
文摘
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Control of lethal poxvirus infection requires NKG2A
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NKG2A limits excessive activation and apoptosis within virus-specific CD8+ T cells
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NKG2C and NKG2E are not expressed on the surface of mouse NK cells and CD8+ T cells
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Qa-1 is preferentially expressed on B cells in ECTV-infected tissues