Caspase-dependent degradation of MDMx/MDM4 cell cycle regulatory protein in amyloid β-induced neuronal damage
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- 作者：Daniel J. Colacurcio ; Jacob W. Zyskind ; Kelly L. Jordan-Sciutto ; Cagla Akay Espinoza ; akayc@upenn.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：MDMx ; MDM4l ; Alzheimer&rsquo ; s disease ; Amyloid β ; Caspase
- 刊名：Neuroscience Letters
- 出版年：2015
- 出版时间：16 November 2015
- 年：2015
- 卷：609
- 期：Complete
- 页码：182-188
- 全文大小：1793 K
文摘
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Age-dependent reduction in MDMx levels in cholinergic neurons in Tg2576 murine model of AD.
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Caspase-dependent degradation of MDMx in neurons exposed to amyloid beta in vitro.