Placental biomarkers of PAH exposure and glutathione-S-transferase biotransformation enzymes in an obstetric population from Tijuana, Baja California, Mexico
Maternal-fetal environment susceptible to toxic exposures at US-Mexico border. Lower serum folate was correlated with higher PAH-DNA adduct levels at birth. Placental DNA adducts in GST mu (-) cord blood were higher than GST(+) genotype. Blood lead levels in Mexican women were higher than reported to NHANES. Cadmium levels in mothers exposed to ETS correlated with total PAH-DNA adducts.