Zinc directly stimulates cholecystokinin secretion from enteroendocrine cells and reduces gastric emptying in rats
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- 作者：Shingo Nakajimaa ; b ; Tohru Hirab ; hira@chem.agr.hokudai.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hitoshi Iwayab ; c ; Hiroshi Harab
- 关键词：Cholecystokinin ; Zinc ; Gastric emptying ; Transient receptor potential ankyrin 1 (TRPA1)
- 刊名：Molecular and Cellular Endocrinology
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：430
- 期：Complete
- 页码：108-114
- 全文大小：1304 K
文摘
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Zinc directly stimulates cholecystokinin (CCK) secretion from CCK-producing cells.
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Extracellular calcium is required for zinc-induced CCK secretion.
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Transient receptor potential ankyrin 1 (TRPA1) mediates zinc-induced CCK secretion.
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Zinc delays gastric emptying through the CCK secretion in rats.