Serotonergic agents act on 5-HT3 receptors in the brain to block seizure-induced respiratory arrest in the DBA/1 mouse model of SUDEP
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- 作者：Carl L. Faingolda ; cfaingold@siumed.edu" class="auth_mail" title="E-mail the corresponding author ; Marcus Randalla ; Chang Zengb ; c ; Shifang Pengc ; Xiaoyan Longd ; Hua-Jun Fengb ; feng.huajun@mgh.harvard.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：5-HT ; SSRIs ; Antagonist ; Audiogenic seizures ; Intracerebroventricular
- 刊名：Epilepsy & Behavior
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：64
- 期：part_PA
- 页码：166-170
- 全文大小：430 K
文摘
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5-HT3 receptor agonist reduces S-IRA in DBA/1 mice.
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5-HT3 receptor antagonist reduces the suppressing effect of fluoxetine on S-IRA.
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Fluoxetine administered into the brain reduces S-IRA.