γ-Promotion of thermal stability and radiolysis mechanism of atenolol β-blocker
详细信息 查看全文
- 作者：Abou-Sekkina ; Morsy M. ; El-Reis ; M.A. ; Aly ; F.A. ; Wassel ; A.A.
- 关键词：γ ; -Radiolysis ; X-ray diffraction ; Compton effect
- 刊名：Thermochimica Acta
- 出版年：2002
- 出版时间：February 7, 2002
- 年：2002
- 卷：383
- 期：1-2
- 页码：37-44
- 全文大小：189 K
文摘
Atenolol (At) β-blocker antihypertensive active ingredient has been investigated for its X-ray diffraction analysis, thermogravimetric analysis (TGA), differential thermal analysis (DTA), IR-absorption spectra and electronic absorption spectra (UV–VIS) before and after exposure to γ-radiation doses. The results obtained indicated high resistance of the material against γ-irradiations. The specific γ-absorbed doses (40 and 60kGy) induced higher resistance to γ-irradiation. Finally the mechanism of γ-radiolysis is putforward and achieved.