Identification and expression patterns of two TRPV channel genes in antennae and Johnston's organ of the dengue and Zika virus vector mosquito, Aedes aegypti

详细信息    查看全文

• 作者：Young-Eun Na^a ; ¹ ; Je Won Jung^b ; ¹ ; Hyung Wook Kwon^b ; ^{hwkwon@inu.ac.kr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：TRPV channels ; Mosquito ; Dengue ; Zika ; Sensory ; Aedes aegypti
• 刊名：Journal of Asia-Pacific Entomology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：19
• 期：3
• 页码：563-569
• 全文大小：1031 K

文摘

Transient Receptor Potential (TRP) channels respond to diverse stimuli and function as primary regulators of sensory information such as olfaction and auditory. TRP proteins are activated by several chemicals and secondary messengers to modulate communications between cell to cell as well as to recognize some environmental changes. Here we report on the identification and localization of the Aedes aegypti homolog of the TRPV channel proteins that is conserved to other insect species based on comparison of amino acids sequences similarities. Transcripts of two TRPV proteins homologous to Drosophila TRPV proteins (Nan and Iav) were ubiquitously expressed in the whole tissues such as antennae, maxillary palps, proboscis, legs, and body of the mosquito. Indeed, TRPV channel family members were localized in sensilla chaetica and sensilla basiconica on the antennae as well as ciliary segment of Johnston's organs. Taken together, we infer that TRPV channels of Aedes aegypti may function as both a sound sensor involved in detection of sound signals and as a chemical sensor responding attractants or repellent compounds allowing them to respond to the appearance of predators or other environmental chemical cues at a distance with behaviors crucial for survival.