Different effects of growth hormone and fasting on the induction patterns of two hormone-sensitive lipase genes in red seabream Pagrus major
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- 作者：Anurak Khieokhajonkheta ; b ; Gen Kanekoa ; agkaneko@mail.ecc.u-tokyo.ac.jp" class="auth_mail" title="E-mail the corresponding author ; kanekog@uhv.edu" class="auth_mail" title="E-mail the corresponding author ; Yuki Hiranoa ; Lu Wanga ; Hideki Ushioa
- 关键词：Adipose tissue ; Lipolysis ; Liver ; Non-esterified fatty acid
- 刊名：General and Comparative Endocrinology
- 出版年：2016
- 出版时间：15 September 2016
- 年：2016
- 卷：236
- 期：Complete
- 页码：121-130
- 全文大小：2670 K
文摘
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Two red seabream hormone-sensitive lipase genes (HSL1 and HSL2) were cloned.
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Ex vivo growth hormone (GH) treatment were performed on liver and adipose tissue.
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GH increased HSL phosphorylation and mRNA levels in both tissues.
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However, GH and fasting induced two HSL isoform genes in different manners.
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Other hormone(s) may contribute to fasting-induced HSL up-regulation.