Longer hypoxia-ischemia periods to neonatal rats causes motor impairments and muscular changes

详细信息    查看全文

• 作者：L.E. Durá ; n-Carabali^a ; ^{luzeled67@gmail.com} ; E.F. Sanches^b ; M.R. Marques^b ; D. Aristimunha^b ; A. Pagnussat^c ; C.A. Netto^a ; ^b
• 关键词：CG ; control group ; CSA ; cross-sectional area ; FiO2 ; fraction of inspired oxygen ; HI ; hypoxia ischemia ; PND ; postnatal day
• 刊名：Neuroscience
• 出版年：2017
• 出版时间：6 January 2017
• 年：2017
• 卷：340
• 期：Complete
• 页码：291-298
• 全文大小：920 K
• 卷排序：340

文摘

180 and 210 min of hypoxia ischemia at postnatal day 3 mimic sensorimotor impairments observed in preterm infants. Hypoxia ischemia causes reduction of cross-sectional area of biceps brachii and tibialis anterior muscle. Striatal volume loss correlates with motor behavior deficits. Lesion to the striatum correlates with muscle alterations after hypoxia ischemia.