Goserelin plus tamoxifen compared to chemotherapy followed by tamoxifen in premenopausal patients with early stage-, lymph node-negative breast cancer of luminal A subtype
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- 作者：Mansoor Alramadhan1 ; Jai Min Ryu1 ; Musaed Rayzah ; Seok Jin Nam ; Seok Won Kim ; Jonghan Yu ; Se Kyung Lee ; Soo Youn Bae ; Sungmin Park ; Hyun-June Paik ; Jeong Eon Lee ; paojlus@hanmail.net" class="auth_mail" title="E-mail the corresponding author
- 关键词：Breast cancer ; Chemotherapy ; Goserelin ; GnRH ; Tamoxifen
- 刊名：The Breast
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：30
- 期：Complete
- 页码：111-117
- 全文大小：691 K
文摘
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Management of premenopausal patients with luminal A breast cancer is controversial.
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Luminal A breast cancer patients are less responsive to chemotherapy.
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Ovarian suppression has no added value over tamoxifen in low risk patient group.
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Low risk luminal A breast cancer patients might be treated with adjuvant tamoxifen alone with good disease control.