Phytochemical composition, antioxidant and cytoprotective activities of essential oil of Salvia lavandulifolia Vahl

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• 作者：Mar铆a Porres-Mart铆nez ; Elena Gonz谩lez-Burgos ; M. Emilia Carretero Accame ; M. Pilar G贸mez-Serranillos
• 关键词：Salvia lavandulifolia Vahl ; Essential oil ; Antioxidant ; U373-MG ; Cytoprotection ; Oxidative stress
• 刊名：Food Research International
• 出版年：November, 2013
• 年：2013
• 卷：54
• 期：1
• 页码：523-531
• 全文大小：867 K

文摘

The use of aromatic plants for food flavoring and medicinal purposes began a long time ago. The chemical composition of two essential oils from Salvia lavandulifolia from Spain differing in plant density conditions (sample S-1 鈥?high density and sample S-2 鈥?low density) was evaluated. Moreover, the antioxidant and cytoprotective effects of both essential oil samples were investigated. The essential oil of S-1 was characterized by a rich content in 1,8-cineole, whereas the essential oil of S-2 contained high amounts of camphor. The two essential oil samples exhibited a potent antioxidant capacity by ROS scavenging, enhancing the endogenous antioxidant system and inhibiting lipid peroxidation in a H₂O₂-induced oxidative stress model in astrocytes. S-1 was the most effective essential oil, suggesting that the higher the plant density, the higher the antioxidant effect.