Mesenchymal stem cells alter macrophage immune responses to Leishmania major infection in both susceptible and resistance mice
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- 作者：Safura Dameshghia ; Ahmad Zavaran-Hosseinia ; zavarana@modares.ac.ir" class="auth_mail" title="E-mail the corresponding author ; Sara Soudia ; Soudi@modares.ac.ir" class="auth_mail" title="E-mail the corresponding author ; Fatemeh Jalali Shirazia ; Shahrzad Nojehdehib ; Seyed Mahmoud Hashemic
- 关键词：Mesenchymal stem cell ; Leishmania major ; Macrophage ; Mouse strain
- 刊名：Immunology Letters
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：170
- 期：Complete
- 页码：15-26
- 全文大小：3628 K
文摘
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Co-culture of macrophages with mesenchymal stem cells modulates their inflammatory behavior.
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The ratio of TNF-α/IL-10 production altered in MSCs co-cultured macrophages in response to L. major.
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BALB/c MSCs induce higher inflammatory ratio compared to C57BL/6 to L. major infection.