The role of FDG-PET/CT imaging in head and neck malignant conditions: Impact on diagnostic accuracy and patient care

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• 作者：Arie Gordin ; Avishay Golz ; Zohar Keidar ; Marcello Daitzchman ; Rachel Bar-Shalom ; Ora Israel
• 刊名：Otolaryngology - Head and Neck Surgery
• 出版年：2007
• 出版时间：July 2007
• 年：2007
• 卷：137
• 期：1
• 页码：130-137
• 全文大小：679 K

文摘

Background

To assess the value of positron emission tomography/computed tomography (PET/CT) with ¹⁸F-Fluorodeoxyglucose (FDG) in patients with head and neck carcinoma as compared with PET and conventional imaging alone, and to assess the impact of PET/CT on further clinical management.

Study Design

Prospective nonrandomized study.

Setting

Ninety patients with head and neck tumors had 107 PET/CT examinations.

Results

The study analysis showed that PET/CT had a sensitivity of 89 % , specificity 95 % , PPV 94 % , NPV 90 % , and accuracy of 92 % . PET/CT altered management in 51 patients (56 % ). PET/CT eliminated the need for previously planned diagnostic procedures in 24 patients, induced a change in the planned therapeutic approach in 21 patients and guided biopsy in 6 patients.

Conclusions

PET/CT is an imaging modality with high diagnostic performance in the assessment of head and neck cancer, and induced a change in further clinical management in more than half of the study population.