Effects of bisphenol analogues on steroidogenic gene expression and hormone synthesis in H295R cells
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- 作者：Yixing Feng ; Zhihao Jiao ; Jiachen Shi ; Ming Li ; Qiaozhen Guo ; Bing Shao ; shaobingch@sina.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Bisphenols analogues (BPF ; BPA ; BPS ; BPAF) ; Steroidogenesis ; Steroidogenic gene ; H295R cell
- 刊名：Chemosphere
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：147
- 期：Complete
- 页码：9-19
- 全文大小：2141 K
文摘
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Assessment the endocrine interrupting action of four bisphenols analogues (BPF, BPA, BPS, BPAF) in H295R cells.
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The rank order of cytotoxicity of four BPs was BPAF > BPA > BPS > BPF.
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Four BPs exhibited endocrine-disrupting action in H295R cell.
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Genes involved in steroidogenesis were altered by four BPs treatments.