Characterization of a Bacillus subtilis surfactin synthetase knockout and antimicrobial activity analysis
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- 作者：Hongxia Liu ; Xiaoxu Qu ; Ling Gao ; Shengming Zhao ; Zhaoxin Lu ; Chong Zhang ; Xiaomei Bie ; bxm43@jiau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：srf genes knockout ; Bacillus subtilis PB2-LS10 ; Transcriptome
- 刊名：Journal of Biotechnology
- 出版年：2016
- 出版时间：10 November 2016
- 年：2016
- 卷：237
- 期：Complete
- 页码：1-12
- 全文大小：2801 K
文摘
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B. subtilis PB2-LS10, a srf genes knockout, exhibits stronger antimicrobial activities than its parental strain.
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The impact of the srf genes deletion on the growth and gene transcriptional profile of the strains were investigated.
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Prominent expression changes in the modified strain involved genes that were essential to metabolic pathways and processes.