Identification of a novel Aleutian mink disease virus B-cell epitope using a monoclonal antibody against VP2 protein
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- 作者：Li Yi ; yili@caas.cn" class="auth_mail" title="E-mail the corresponding author ; Yuening Cheng ; Miao Zhang ; Zhigang Cao ; Mingwei Tong ; Shipeng Cheng ; tcscsp@126.com" class="auth_mail" title="E-mail the corresponding author ; Xijun Yan
- 关键词：Aleutian mink disease virus ; VP2 protein ; Monoclonal antibody ; B-cell epitope
- 刊名：Virus Research
- 出版年：2016
- 出版时间：2 September 2016
- 年：2016
- 卷：223
- 期：Complete
- 页码：39-42
- 全文大小：1212 K
文摘
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386HLQQNFSTRYIYD398 is a linear B-cell epitope of the AMDV VP2 protein.
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Sequence alignments demonstrated that linear epitope is highly conserved among AMDV strains except 386H, and less conserved among Raccoon dog amdovirus, Gray fox amdovirus, Red fox amdovirus, Bat parvovirus and Mink enteritis parvovirus.
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The identified epitope can be recognized by AMDV positive serum, it may be useful for clinical applications.