Shorter telomeres in adults with Type 1 diabetes correlate with diabetes duration, but only weakly with vascular function and risk factors
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- 作者：Andrzej S. Januszewskia ; b ; 1 ; Surya S. Sutantoc ; 1 ; Susan McLennanc ; d ; David N. O&rsquo ; Nealb ; Anthony C. Keecha ; Stephen M. Twiggc ; d ; 2 ; Alicia J. Jenkinsa ; b ; 2 ; alicia.jenkins@ctc.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：Type 1 diabetes ; Telomere ; Complications
- 刊名：Diabetes Research and Clinical Practice
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：117
- 期：Complete
- 页码：4-11
- 全文大小：382 K
文摘
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Cross-sectional study of telomeres in Type 1 diabetes and non-diabetic subjects.
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Shorter telomeres in T1D vs. non-diabetic subjects.
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Relative telomere length (RTL) do not correlate with HbA1c, oxidation or smoking.
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RTL correlates inversely with age, T1D duration, inflammation and vascular function.