Intramolecular palladium mediated 蟺-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines

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• 作者：Zainab Al-Shuhaib ; Henning B枚ckemeier ; Lawrence Coghlan ; Elina D枚rksen ; Iestyn V. Jones ; Patrick J. Murphy ; Robert Nash ; James M. Page
• 关键词：UUUWQKPIIYCXRO-RDNYARLASA-N
• 刊名：Tetrahedron Letters
• 出版年：4 December, 2013
• 年：2013
• 卷：54
• 期：49
• 页码：6716-6718
• 全文大小：369 K

文摘

The Pd-mediated 蟺-allyl cyclisation of bis-Cbz- and bis-Boc-protected guanidines 4 and 14b led to the formation of five- and six-membered heterocycles 5 and 17 in high yields.